Debut | Silk fibroin slow absorption repair material

Recently, at the "14th Southern Hernia Forum" held in Shenzhen, Guangdong, a new type of slow-absorption repair material caught people's eyes. At the forum, the live broadcast of over 20 teaching surgeries was a stunning spectacle, watched by tens of thousands of people. Among them, the first show was particularly impressive.

Although our editor has heard about this world-first slow-absorption silk fibroin supplement material with Chinese characteristics and oriental quality, it has always been like "only hearing the sound of footsteps on the stairs, but not seeing anyone coming down". At this Southern Hernia Forum, we finally got to see its "true face".

This debut was personally presented by Professor Chen Shuang, the chairman of the forum, and his top disciple Professor Li Yingru in the operating room of Shenzhen Bao'an District People's Hospital, with sincere interpretation.

The humorous and witty demeanor of Professor Chen on stage, coupled with the bold questioning and witty remarks of Professor Tan Min, the host, made for a memorable event. It still lingers in my mind to this day.

The patient undergoing surgical teaching was a 24-year-old unmarried male from the local area who had suffered from inguinal hernia for many years, specifically a scrotal hernia. Professor Chen said that this unmarried and unfertile male patient with inguinal hernia was very suitable for using this new type of fully absorbable material. The silk fibroin hernia repair mesh is a self-developed, slow-absorption repair material in China. The so-called slow absorption means that it takes about two years to be fully absorbed, which is perfectly suitable for the repair of inguinal hernia.

The engineering and technical personnel of the patch told me: The silk fibroin slow-absorption repair material is derived from silk. The "silk thread" used in previous surgeries was also made of silk. The silk thread used in the past did not absorb because of the presence of sericin components surrounding the silk. However, pure silk fibroin material can be slowly absorbed by the body.

The silk fibroin slow-absorption repair material is currently developed and produced by Zhejiang Xingyue Biotechnology Co., Ltd., which is affiliated with the Zhejiang Provincial Key Enterprise Research Institute of Medical Materials and Tissue Engineering. The company possesses independent intellectual property rights. For this material, the National Medical Products Administration industry standard (YY/T 1950-2024) titled "Tissue Engineering Medical Devices - Silk Fibroin", drafted by Zhejiang University, Xingyue Biotechnology, and other institutions, has been officially approved and is set to be officially released in the latter half of this year. Currently, the company is collaborating with the domestic listed company "Dabo Medical" for promotion.

According to relevant data, this product embodies Chinese characteristics, with silk further reflecting the culture of Eastern civilization. Medical silk materials exhibit excellent mechanical properties and biocompatibility. Silk does not contain cellular DNA components and has extremely low immunogenicity. Its warp-knitted porous structure facilitates rapid ingrowth of cellular vascular tissue, slowly degrades in the body, and ultimately achieves repair through the body's regenerative tissues. Before the product was launched, with the assistance of relevant hospitals, over 140 inguinal hernia surgeries were conducted, and after a 2-year follow-up, not a single case of hernia recurrence occurred, meeting the design requirements.

The debut at the "14th Southern Hernia Forum" was also highly successful. Continuous follow-up visits have been conducted for the patient who underwent surgery using silk fibroin slow-absorption repair materials. The patient was discharged the next day and reported feeling well. There were no complications such as seroma or hematoma. A B-ultrasound examination was conducted one week post-surgery, and all results were normal.

Our team will continue to follow up on the situation.

I wish the domestically produced absorbable materials can develop rapidly and meet China's needs.

Article source: Southern Hernia Forum official account